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Ticker
Investor Class
BIPIX
Service Class
BIPSX

CUSIP
Investor Class
743185-480
Service Class
743185-472


Fund Number
Investor Class
043
Service Class
073


Inception Date
6/19/2000


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Votes

Vital Statistics

Class Ticker CUSIP Fund Number
Investor BIPIX 743185-480 043
Service BIPSX 743185-472 073

Inception Date for all share classes is 6/19/2000

NAV
as of 1/5/2009

Class NAV % Change $ Change
Investor $51.49 -0.46% -$0.24
Service $47.41 -0.48% -$0.23
At a GlanceThe Biotechnology UltraSector ProFund provides leveraged exposure to the Dow Jones U.S. Biotechnology Index. ObjectiveSeeks daily investment results, before fees and expenses, that correspond to 150%, of the daily performance of the Dow Jones U.S. Biotechnology Index.

There is no guarantee that any ProFund will achieve its investment objective. Investment return and principal value will vary and shares may be worth more or less at redemption than at original purchase. See the prospectus for more information.

This ProFund routinely employs leveraged investment techniques that magnify gains and losses and result in greater volatility in value.

This ProFund invests in a single industry. Its shares do not represent a complete investment program. As non-diversified and single industry fund, the value of its shares may fluctuate more than shares invested in a broader range of industries and companies.
Dow Jones U.S. Biotechnology Index
The Dow Jones U.S Biotechnology Index measures the performance of the biotechnology industry of the U.S. equity market. Component companies include those engaged in genetic research, and/or the marketing and development of recombinant DNA products. Makers of artificial blood and contract biotechnology researchers are also included in the Index. It is not possible to invest directly in an index.
Index (as of 9/30/2008)
Top 10 Index Companies
Name Weight
Amgen Inc. 23.37%
Gilead Sciences Inc. 15.63%
Genentech Inc. 15.32%
Celgene Corp. 10.73%
Genzyme Corp. 8.05%
Biogen Idec Inc. 5.50%
Vertex Pharmaceuticals Inc. 1.74%
Illumina Inc. 1.73%
ImClone Systems Inc. 1.43%
Charles River Laboratories International Inc. 1.41%
Total Index Companies
36
Average Index Market Capitalization
7.45 billion
Returns (as of 9/30/2008)
Past performance does not guarantee future results. The performance data quoted represents past performance and current returns may be lower or higher. The investment return and principal value of an investment will fluctuate so that an investor's shares, when redeemed may be worth more or less than the original cost. For standardized returns as of the most recent month-end, click here.

Returns include the reinvestment of dividends and capital gains.

YTD (as of 1/5/2009) 1.98%
Average Annual One Year 1.51%
Average Annual Three Year 1.15%
Average Annual Five Year 9.05%
Average Annual Ten Year ––
Average Annual Since Inception -6.26%
Cumulative Since Inception -41.48%
Gross Expense Ratio 1.60%
Net Expense Ratio ––

Fund Statistics
Limits On Exchanges None
Minimum Investment
Individual Investor $15,000
Financial Professionals $5,000

All data, unless otherwise noted, is as of 9/30/2008 and for Investor Class Shares only and is subject to change.

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Investing in ProFunds involves certain risks, including in all or some cases, leverage, liquidity, concentration, non-diversification, foreign investment, foreign currency, high yield, interest rate, credit, market, correlation, aggressive investment technique and repurchase agreement risks. Moreover, there is no guarantee that any ProFund will achieve its investment objective. These risks can increase volatility and decrease performance. All ProFunds permit active investment strategies which can decrease performance and increase expenses.
 


Carefully consider the investment objectives, risks, charges and expenses of ProFunds before investing or sending money. This and other information can be found in their prospectuses. Read the prospectus carefully before investing. For a ProFunds prospectus, please call 888-PRO-FNDS (888-776-3637), or visit www.profunds.com. Financial professionals should call 888-PRO-5717 (888-776-5717).


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